Arrhythmias & electrophysiology

Lesion Durability of the Second Generation Pentaspline Pulsed Field Ablation Catheter NAVIGATE-PF Phase 2 Results

Circ Arrhythm ElectrophysiolPublished first-in-human study

Authors' conclusion

By facilitating real-time visualization of catheter positioning and acute lesion estimation through tags, the second-generation map-and-ablate pentaspline PFA catheter and integrated mapping system may enhance procedural success.

Study context

Population
Patients with atrial fibrillation undergoing ablation with the second-generation, mapping-integrated pentaspline pulsed field ablation (PFA) catheterindex ablation, remaps performed in 17 patients
Participants
20 patients
Outcome
Lesion durability by invasive remapping
Follow-up
60 days post index procedure
Methodological detailsinvasive remapping
  • Invasive remapping

Main finding

As reported in the abstract

Pulmonary veins

95%

Posterior wall

86%

Original publication

Lesion Durability of the Second Generation Pentaspline Pulsed Field Ablation Catheter NAVIGATE-PF Phase 2 Results. Circ Arrhythm Electrophysiol. Published 1 April 2026. doi:10.1161/circep.125.014477

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.