Arrhythmias & electrophysiology
Visualization of Pulsed Field Ablation (PFA) During PVI With the Second-Generation Pentaspline Catheter: NAVIGATE-PF Phase 1 Results
Authors' conclusion
The second-generation pentaspline PFA catheter, with dynamic shape visualization and preview of anticipated electric field, resulted in alignment with postablation voltage mapping.
Study context
- Population
- AF patients undergoing PVI with the second-generation pentaspline PFA catheter15 in acute tags analysis
- Participants
- 30 patients
- Outcome
- Estimated shape and position of acute tags relative to low-voltage borders on high-density postablation maps
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Post-procedural
Distance between tag and low-voltage border
−0.58 mm
Q1-Q3: −2.9 to 2.17 mm
Further findings
Successful treatment with the second-generation PFA catheter
- All 30 patients successfully treated
Original publication
Visualization of PFA During PVI With the Second-Generation Pentaspline Catheter: NAVIGATE-PF Phase 1 Results. JACC Clin Electrophysiol. Published 30 December 2025. doi:10.
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