Arrhythmias & electrophysiology
Leveraging a randomized trial to assess relationships between transeptal puncture, brain emboli, and migraine symptoms
Authors' conclusion
Transseptal puncture was not associated with visual auras; however, acute brain emboli involving the visual cortex were associated with such symptoms.
Study context
- Population
- Patients undergoing catheter ablation for ventricular arrhythmias
- Participants
- 63 vs 57
- Comparison
- Transseptal vs Retrograde aortic
- Transseptaln = 63
- Retrograde aorticn = 57reference
- Primary endpoint
- Postablation migraine-related visual auras (validated migraine assessment)
- Follow-up
- 1 month
Primary result
As reported in the abstract
Postablation visual auras
P = 0.78
Further findings
Migraine-related visual auras by acute brain emboli in occipital or parietal lobes (MRI)
P < 0.01
Migraine-related visual auras by acute brain emboli in occipital or parietal lobes (MRI)
- After multivariable adjustment, acute brain emboli associated with 12-fold greater odds of visual auras
Original publication
Leveraging a randomized trial to assess relationships between transeptal puncture, brain emboli, and migraine symptoms. Heart Rhythm. Published 7 July 2025. doi:10.
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