‘Life’s Essential 8’ cardiovascular health with premature cardiovascular disease and all-cause mortality in young adults: the Kailuan prospective cohort study
Authors' conclusion
We observed an inverse gradient association of baseline and long-term CVH with the risk of premature CVD and all-cause mortality in young adults
Study context
- Population
- Cardiovascular disease (CVD)-free young Chinese adults aged 18–40 years, Kailuan cohort
- Participants
- 16,011 adults
- Exposure
- Low vs high cardiovascular health (CVH)
- Outcome
- Premature CVD and all-cause mortality
- Follow-up
- Median 13 years
Main finding
As reported in the abstract
Low CVH vs High CVHAdjusted hazard ratio (95% CI)
CVD, baseline CVH
7.34(3.19–16.89)
All-cause mortality, baseline CVH
2.54(1.27–5.06)
CVD, time-updated CVH
4.38(2.14–8.97)
All-cause mortality, time-updated CVH
1.99(1.06–3.71)
CVD, time-varying CVH
8.19(2.70–24.88)
All-cause mortality, time-varying CVH
4.28(1.70–10.81)
- CVD cases
- 271 (1.7%)
- All-cause mortality cases
- 219 (1.4%)
Observational data: associations, not effects.
Original publication
‘Life’s Essential 8’ cardiovascular health with premature cardiovascular disease and all-cause mortality in young adults: the Kailuan prospective cohort study. Eur J Prev Cardiol. Published 9 February 2023. doi:10.
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