Life’s Essential 8 score and SCORE2 for cardiovascular risk prediction in a middle-aged cohort from the general population: the Akershus Cardiac Examination 1950 Study
Authors' conclusion
LE8 can be used in health promotion based on prognostic value comparable to SCORE2, for counselling to a healthier lifestyle to preserve cardiovascular health.
Study context
- Population
- Men and women born in 1950 residing in Akershus County, Norway, without established cardiovascular disease (CVD)3,706 participants
- Participants
- 2,938 men
- Exposure
- LE8 vs SCORE2 for CVD risk prediction
- Outcome
- Incident MACE
- Follow-up
- Median 8.3 years
Methodological detailsbirth cohort
- Birth cohort
Main finding
As reported in the abstract
MACE prediction
| Group | HR |
|---|---|
| LE8 | 1.53 (95% CI 1.35-1.73) |
| SCORE2 | 1.82 (95% CI 1.57-2.10) |
HR
LE81.53 (95% CI 1.35-1.73)
SCORE21.82 (95% CI 1.57-2.10)
- LE8 vs SCORE2: p for comparison = 0.30 — comparable predictive performance
- Incident major adverse cardiovascular events (MACE)
- 6.7%
Observational data: associations, not effects.
Further findings
- "Optimal" cardiovascular health (CVH)
- 9.8%
- Mean SCORE2
- 6.1
- Mean LE8 score
- 63.9
Original publication
Life’s Essential 8 score and SCORE2 for cardiovascular risk prediction in a middle-aged cohort from the general population: the Akershus Cardiac Examination 1950 Study. Eur J Prev Cardiol. Published 7 June 2026. doi:10.
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