Lipoprotein(a), atherosclerotic plaque burden, and long-term cardiovascular outcomes in patients with coronary artery disease
Authors' conclusion
Among patients with established ASCVD, Lp(a) was associated with plaque burden, supporting evidence that relates Lp(a) to atherosclerotic disease. However, Lp(a) was not associated with long-term mortality or cardiac adverse events in these patients.
Study context
- Population
- Patients undergoing coronary angiography for stable angina or ACS
- Participants
- 798 patients
- Comparison
- Lp >125 nmol/L vs lower Lp
Methodological detailsIntravascular ultrasound (IVUS) and near-infrared spectroscopy of a non-culprit segment
- IVUS and near-infrared spectroscopy of a non-culprit segment
Pooled result
As reported in the abstract
IVUS plaque burden; long-term clinical outcomes
Lp(a) vs Lp(a) ≤125 nmol/LHazard ratio (95% CI)P value
5-year MACE
1.06(0.70–1.60)
P = 0.7810-year all-cause mortality
0.63(0.38–1.06)
P = 0.78Original publication
Lipoprotein(a), atherosclerotic plaque burden, and long-term cardiovascular outcomes in patients with coronary artery disease. Eur J Prev Cardiol. Published 12 March 2026. doi:10.
Summarised from the published abstract; every number is checked against it