Arrhythmias & electrophysiology

Localized Re-Entry Is a Frequent Mechanism of De Novo Atypical Flutter

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

Atypical atrial flutters in patients without prior surgery or complex ablation are often due to localized re-entry (approximately 50% in the LA and a higher frequency in the RA).

Study context

Population
Patients undergoing catheter ablation of de novo atypical atrial flutter (no prior ablation or surgery)flutters in 62 patients
Participants
85 patients
Exposure
Left atrium (LA) vs right atrium (RA)
  • LAn = 58
  • RAn = 27
Outcome
Location and mechanism of atypical flutter

Main finding

As reported in the abstract

Flutter mechanism by atrium
GroupValueMacro-re-entryLocalized re-entry
LA50%29 (50%)29 (50%)
RA70%8 (30%)19 (70%)

Value

LA50%
RA70%

Macro-re-entry

LA29 (50%)
RA8 (30%)

Localized re-entry

LA29 (50%)
RA19 (70%)
  • LA vs RA: P = 0.08
Both localized and macro-re-entrant flutters
Nine patients

Observational data: associations, not effects.

Further findings

Recurrent atrial arrhythmias after ablation · 39.4 months (Q1-Q3: 18.2-65.8 months)

After a single ablation
66%
After >1 ablation
50%

Different circuits or arrhythmias vs index arrhythmia at repeat ablation

Different tachycardia circuits or arrhythmias
13 of 18 cases (72%)

Original publication

Localized Re-Entry Is a Frequent Mechanism of De Novo Atypical Flutter. JACC Clin Electrophysiol. Published 6 December 2023. doi:10.1016/j.jacep.2023.10.026

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