Heart failure & cardiomyopathies
Long-term cardiovascular outcomes among immigrants and non-immigrants in cardiac resynchronization therapy: a nationwide study
Authors' conclusion
No overall differences in efficacy of CRT in improving outcomes between immigrants and non-immigrants were identified.
Study context
- Population
- Patients with heart failure (HF) undergoing first-time cardiac resynchronization therapy (CRT) implantation in Denmark, 2000–2017
- Participants
- 369 vs 7,855
- Exposure
- Immigrants vs non-immigrants after CRT
- Immigrantsn = 369
- Non-immigrantsn = 7,855reference
- Outcome
- HF-related hospitalizations and all-cause mortality
- Follow-up
- Up to 5 years
Methodological detailsnationwide registries, Follow-up up to 5 years; Cox regression analyses
- Nationwide registries
- Follow-up up to 5 years; Cox regression analyses
Main finding
5-year all-cause mortality
Hazard ratio
1.2
95% CI 0.8–1.7
P = 0.50
By group
Immigrantsvs Non-immigrants
HR 1.2 (95% CI 0.8–1.7); P = 0.50
As reported in the abstract
Observational data: associations, not effects.
Further findings
HF-related hospitalizations, year before vs year after CRT
Year before CRT
Year after CRT
CV causes of death (share of deaths)
| Outcome | HR (95% CI) | |
|---|---|---|
| Mortality, immigrants of Middle Eastern origin (subgroup)Middle Eastern immigrantsvs Non-immigrants | 2.2 (1.2–4.1) | |
| 0.20.5125Hazard ratio (log scale) |
HF-related hospitalizations, year before vs year after CRT
- Consistent reduction in HF-related hospitalizations in both groups
HF guideline-directed pharmacotherapy before and after CRT
- Similar high uptake in both groups
Original publication
Long-term cardiovascular outcomes among immigrants and non-immigrants in cardiac resynchronization therapy: a nationwide study. Europace. Published 19 June 2023. doi:10. 1093/ europace/ euad148
Composed by AI from the published abstract and checked against it. How Briefs are made →