Long-term clinical outcomes of percutaneous coronary intervention for ostial left main coronary artery disease
Authors' conclusion
PCI treatment for ostial LM lesions achieved favourable long-term outcomes, with a similar MI risk compared with the mid-shaft group but a significantly lower risk of MI compared with the distal group.
Study context
- Population
- Patients with left main (LM) coronary disease, Fuwai Hospital, January 2004–December 2016
- Participants
- 4,625 patients
- Exposure
- Ostial vs shaft vs bifurcation LM lesions treated with percutaneous coronary intervention (PCI)
- Ostialn = 627
- Outcome
- TVF (cardiac death, target vessel MI and target vessel revascularisation)
- Follow-up
- 3 years
Methodological detailssingle-centre, registry
- Single-centre
- Registry
Main finding
As reported in the abstract
3-year TVF (DES implantation)
Ostial
7.5%
44
Observational data: associations, not effects.
Further findings
Female sex
| Outcome | Ostial | Shaft | Bifurcation | P value |
|---|---|---|---|---|
| MIOstial vs Bifurcation · also for MI originating in LM vessel (p=0.02) | 2.0% | — not stated in the abstract | 4.2% | P = 0.02 |
— not stated in the abstract
- Female sex: p<0.0001
Predictors of long-term cardiac death or myocardial infarction (MI) (ostial LM PCI)
- Procedural complications an independent risk factor; more recent PCI protective
Original publication
Long-term clinical outcomes of percutaneous coronary intervention for ostial left main coronary artery disease. EuroIntervention. Published 24 April 2023. doi:10.
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