Aortic & peripheral vascular diseaseCohort study

Long-term exposure to wildfire smoke particulate matter and incident stroke: a US nationwide study

Eur Heart JPublished

  • Prospective open cohort study
  • national
  • Medicare Fee-for-Service

Authors' conclusion

This study provides national-scale evidence that chronic exposure to wildfire smoke PM2.5 increases stroke risk in older adults.

Study context

Population
Medicare Fee-for-Service beneficiaries aged ≥65 years, US, 2007–2018∼2.9 million incident strokes
Participants
∼25 million beneficiaries
Exposure
Per 1 µg/m3 increase in long-term wildfire smoke PM2.5 exposure
Outcome
Incident stroke

Main finding

As reported in the abstract

Incident stroke per 1 µg/m3 increase in 3-year average wildfire smoke PM2.5 · 3-year average exposure

Hazard ratio

1.013

95% CI 1.006–1.020

Per 1 µg/m3 increase in wildfire smoke PM2.5
HR 1.013 (95% CI 1.006–1.020)

Per 1 µg/m3 increase in wildfire smoke PM2.5, as printed

Observational data: associations, not effects.

Original publication

Long-term exposure to wildfire smoke particulate matter and incident stroke: a US nationwide study. Eur Heart J. Published 27 January 2026. doi:10.1093/eurheartj/ehaf875

Summarised from the published abstract; every number is checked against it