Aortic & peripheral vascular disease
Long-term outcomes of peripheral atherectomy for femoropopliteal endovascular interventions
Authors' conclusion
The use of atherectomy during femoropopliteal artery PVI was not associated with an increase in the risk of long-term adverse safety outcomes among patients with peripheral artery disease.
Study context
- Population
- Medicare fee-for-service beneficiaries undergoing femoropopliteal artery PVI, 2015–201859,142 (35.1%) atherectomy
- Participants
- 168,553 beneficiaries
- Exposure
- Atherectomy vs no atherectomy during femoropopliteal PVI
- Atherectomyn = 59,142
- Outcome
- Long-term safety: composite of death and amputation; major adverse limb events
- Follow-up
- Median 993 days (IQR 319-1,377 days)
Methodological detailsinverse probability of treatment weighting, Medicare 100% sample
- Inverse probability of treatment weighting
- Medicare 100% sample
Main finding
As reported in the abstract
median follow-up 993 days
Atherectomy vs No atherectomyAdjusted hazard ratio (95% CI)P value
Death and amputation
0.99(0.97–1.01)
P = 0.19Major adverse limb events
1.02(0.99–1.05)
P = 0.26Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | P value | |
|---|---|---|---|
| Amputation or surgical revascularisation | 0.92 (0.90–0.94) | P < 0.01 | |
| Subsequent PVI | 1.19 (1.16–1.21) | P < 0.01 | |
| 0.512Adjusted hazard ratio (log scale) |
Original publication
Long-term outcomes of peripheral atherectomy for femoropopliteal endovascular interventions. EuroIntervention. Published 3 April 2023. doi:10.
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