Long-Term Gender Disparities in New-Onset Heart Failure After Acute Coronary Syndrome
Main finding · New-onset HFResult — go to the resultHazard ratio 1.22 95% CI 1.03–1.44Authors' conclusion
Following ACS, males experienced a greater long-term risk of developing new-onset HF as compared with females.
Study context
- Population
- Acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI), large-scale databaseafter propensity matching
- Participants
- 3,334 patients
- Exposure
- Males vs females after ACS treated with PCI
- Outcome
- New-onset heart failure (HF)
- Follow-up
- 5 years
Methodological detailspropensity-score matched
- Propensity-score matched
Main finding
As reported in the abstract
Hazard ratio
1.22
95% CI 1.03–1.44
P = 0.02
By group
Malesvs Females
HR 1.22 (95% CI 1.03–1.44); P = 0.02
Observational data: associations, not effects.
Secondary outcomes
All-cause mortality · 5 years
- On landmark analysis, mortality differences emerged after the first year and were maintained thereafter
- Propensity-score matched
Ischaemic outcomes (MI, re-PCI, ischaemic stroke) · 5 years
- Ischaemic outcomes were comparable between cohorts
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Long-Term Gender Disparities in New-Onset Heart Failure After Acute Coronary Syndrome. ESC Heart Fail. Published 5 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →