Valvular & structural heart disease
Long-Term Outcomes of Contemporary Surgical Repair for Degenerative Mitral Regurgitation
Authors' conclusion
This contemporary series provides further data on the low in-hospital mortality and excellent long-term outcomes of surgical mitral repair when performed in a high-volume center.
Study context
- Population
- Patients undergoing surgical mitral repair for degenerative mitral regurgitation at a tertiary care center, 2008–2017
- Participants
- 3,317 patients
- Outcome
- Long-term survival, reinterventions and HF rehospitalizations
- Follow-up
- 10 years
Methodological detailssingle-centre, high-volume tertiary care center, independently adjudicated outcomes
- Single-centre
- High-volume tertiary care center
- Independently adjudicated outcomes
Main finding
As reported in the abstract
10-year survival
89.65%
95% CI 88.75%–90.55%
Freedom from reoperation at 10 years
96.63%
95% CI 95.63%–97.63%
10-year freedom from HF rehospitalization
92.24%
95% CI 90.62%–93.86%
Observational data: associations, not effects.
Further findings
In-hospital mortality
- All cases (16 of 3,317)
- 0.48%
- Isolated mitral valve repair (5 of 2,399)
- 0.21%
Independent risk factors
- Survival: preoperative symptoms and anterior leaflet disease
- Reoperation: anterior leaflet disease, second run of cardiopulmonary bypass, more than mild mitral regurgitation at discharge
- HF rehospitalization: age, prior HF hospitalization, preoperative symptoms, anterior leaflet disease
Original publication
Long-Term Outcomes of Contemporary Surgical Repair for Degenerative Mitral Regurgitation. J Am Coll Cardiol. Published 5 February 2025. doi:10.
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