Coronary disease & ACS

Long-Term Survival Advantage of Total Arterial Revascularization in Elderly Patients Following Coronary Artery Bypass Grafting

JACC AdvPublished Retrospective cohort study

Authors' conclusion

TAR improves long-term survival in both elderly and younger patients.

Study context

Population
Patients undergoing primary isolated CABG with at least 2 grafts, 2001–2020, binational cardiac surgery registry
Participants
59,641 patients
Exposure
Total arterial revascularization (TAR) vs non-TAR grafting in elderly and younger patients
Outcome
Long-term all-cause mortality
Methodological detailsbinational registry, inverse probability treatment weighting
  • Binational registry
  • Inverse probability treatment weighting

Main finding

As reported in the abstract

Long-term survival, by age group
TAR vs Non-TARHazard ratio (95% CI)P value
Elderly (≥70 years)
0.87(0.81–0.92)
P < 0.001
Younger (<70 years)
0.80(0.73–0.88)
P < 0.001

Observational data: associations, not effects.

Further findings

Survival, non-TAR split into multiple vs single arterial grafting

Survival hierarchy: highest with TAR, then non-TAR-multiple arterial grafting, lowest with non-TAR-single arterial grafting

Original publication

Long-Term Survival Advantage of Total Arterial Revascularization in Elderly Patients Following Coronary Artery Bypass Grafting. JACC Adv. Published 8 October 2025. doi:10.1016/j.jacadv.2025.102226

Summarised from the published abstract; every number is checked against it

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