Coronary disease & ACSCohort study
Multiple arterial vs. single arterial coronary artery bypass grafting: sex-related differences in outcomes
- Retrospective cohort study
- inverse probability weighted
- sex-stratified
Authors' conclusion
Compared to single arterial grafting, multiple arterial revascularization is associated with improved long-term survival for women as well as men.
Study context
- Population
- Adults receiving at least two grafts in primary isolated CABG, Australian and New Zealand Society of Cardiothoracic Surgical Database, 2001–202010,693 (19.7%) female
- Participants
- 54,275 adults
- Exposure
- Multiple arterial grafting vs Single arterial grafting
- Multiple arterial graftingn = 29,711
- Outcome
- All-cause mortality
Main finding
As reported in the abstract
All-cause mortality, by sex (sex-stratified, IPW Cox)
Interaction: insignificant subgroup effect from sex on the survival advantage
P = .08
Observational data: associations, not effects.
Further findings
Sex-stratified subgroups
- Survival benefit consistent across all sex-stratified subgroups except women with left main coronary disease
Original publication
Multiple arterial vs. single arterial coronary artery bypass grafting: sex-related differences in outcomes. Eur Heart J. Published 31 May 2024. doi:10.1093/eurheartj/ehae294
Summarised from the published abstract; every number is checked against it