Longitudinal cardiac imaging for assessment of myocardial injury in non-hospitalised community-dwelling individuals after COVID-19 infection: the Rotterdam Study
Authors' conclusion
Almost all recovered non-hospitalised COVID-19 participants had normal CMR-derived ventricular volumes and function, without relevant myocardial injury.
Study context
- Population
- Non-hospitalised community-dwelling adults who recovered from COVID-19 at home within 2 years prior to inclusion, Rotterdam Study
- Participants
- 92 adults
- Exposure
- Persistent post-COVID-19 cardiac symptoms vs no persistent symptoms; pre- vs post-COVID-19 echocardiography
- Outcome
- Myocardial injury and myocardial function on CMR and echocardiography after COVID-19 infection
Methodological detailspopulation-based
- Population-based
Main finding
As reported in the abstract
Normal post-COVID-19 CMR findings
- Normal cardiovascular magnetic resonance (CMR)-derived left ventricular (LV) function
- 92%
- Normal CMR-derived RV EF
- 98%
- Normal native T1 relaxation times
- 100%
- Normal extracellular volume
- 98%
- Normal T2 relaxation times
- 98%
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted mean change (%) (95% CI) | |
|---|---|---|
| Pre- vs post-COVID-19 echocardiographyPost-COVID-19vs Pre-COVID-19LVEF; age- and sex-adjusted | −1.37 (−2.57% to −0.17%) | |
| Pre- vs post-COVID-19 echocardiographyPost-COVID-19vs Pre-COVID-19Global longitudinal strain; age- and sex-adjusted | 1.32 (0.50%–2.15%) | |
| −4−2024Difference, % (linear scale) |
CMR-derived ventricular volumes, LV function, myocardial injury by persistent symptoms
- No significant differences between participants with and without persistent symptoms
Original publication
Longitudinal cardiac imaging for assessment of myocardial injury in non-hospitalised community-dwelling individuals after COVID-19 infection: the Rotterdam Study. Heart. Published 16 January 2025. doi:10.
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