Impact of Mandatory Preoperative Dental Screening on Infective Endocarditis in Patients Undergoing Surgical Valve Replacement
Authors' conclusion
Risk of IE was low regardless of PDS practice. MPDS prior to surgery did not alter the risk of IE or all-cause mortality in patients undergoing SVR in Denmark.
Study context
- Population
- Patients undergoing surgical valve replacement (SVR) in Western Denmark from 2020 to 2022patients undergoing SVR, 370 propensity score-matched patients
- Participants
- 1,207 patients
- Exposure
- Mandatory preoperative dental screening (MPDS) vs NPDS
- MPDSn = 805
- NPDSn = 402
- Outcome
- Incidence of IE
- Follow-up
- Median 2.6 years
Methodological detailsDanish registries, adjudicated using medical records, propensity score-matched
- Danish registries
- Adjudicated using medical records
- Propensity score-matched
Main finding
As reported in the abstract
- Developed infective endocarditis (IE) (all patients)
- 3.3% (n = 40)
Observational data: associations, not effects.
Secondary outcomes
Subsequent PDS
| Outcome | MPDS | NPDS |
|---|---|---|
| All-cause mortality (secondary) · 2 years | 2-year mortality 6.2% (95% CI 4.7–8.1) | 2-year mortality 2.8% (95% CI 1.6–5.0) |
- All-cause mortality (secondary): Difference abolished in 370 propensity score-matched patients
Baseline characteristics
- Patients in the MPDS were older with higher rates of coexisting comorbidities
Composite of IE and all-cause mortality (secondary)
- Difference not abolished in propensity score-matched patients
Original publication
Impact of Mandatory Preoperative Dental Screening on Infective Endocarditis in Patients Undergoing Surgical Valve Replacement. JACC Adv. Published 16 January 2025. doi:10.
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