Arrhythmias & electrophysiology
Longitudinal risk of death, hospitalizations for atrial fibrillation, and cardiovascular events following catheter ablation of atrial fibrillation: a cohort study
Authors' conclusion
Patients undergoing AF ablations had good long-term survival, a low incidence of rehospitalizations for stroke or heart failure, and about half remained free of rehospitalizations for AF or flutter, including for repeat AF ablation, or cardioversion.
Study context
- Population
- Patients undergoing AF ablation in Australia and New Zealand, 2008–2017 (mean age 62.7 ± 11.8 years, 30.0% female)124 858.7 person-years follow-up
- Participants
- 30,601 patients
- Outcome
- All-cause mortality and rehospitalizations for AF or flutter, repeat AF ablation, and cardioversion
Methodological detailsnationwide hospitalization data
- Nationwide hospitalization data
Main finding
As reported in the abstract
All-cause mortality; rehospitalization for AF or flutter, repeat AF ablation, cardioversion
- Deaths during 124 858.7 person-years of follow-up
- 1900
- Mortality incidence rate
- 1.5/100 person-years
- Survival probability by 5 years
- 93.0% (95% CI 92.6-93.4%)
- Survival probability by 10 years
- 84.0% (95% CI 82.4-85.5%)
- Rehospitalization for AF or flutter, incidence rate
- 13.3/100 person-years
- Repeat ablation, incidence rate
- 5.9/100 person-years
- Cardioversion, incidence rate
- 4.5/100 person-years
- Rehospitalization for AF or flutter, cumulative incidence at 10 years
- 49.4% (95% CI 48.4-50.4%)
- Repeat ablation, cumulative incidence at 10 years
- 28.1% (95% CI 27.2-29.0%)
- Cardioversion, cumulative incidence at 10 years
- 24.4% (95% CI 21.5-27.5%)
Observational data: associations, not effects.
Secondary outcomes
Rehospitalizations for other CV events
- Stroke
- 0.7/100 person-years
- HF
- 1.1/100 person-years
- Acute MI
- 0.4/100 person-years
- Syncope
- 0.6/100 person-years
- Other arrhythmias
- 2.5/100 person-years
- New cardiac device implantation
- 2.0/100 person-years
Outcomes by age, sex and HF
- Elderly patients and those with comorbid HF had worse survival but were less likely to undergo repeat ablation
- Long-term outcomes comparable between the sexes
Original publication
Longitudinal risk of death, hospitalizations for atrial fibrillation, and cardiovascular events following catheter ablation of atrial fibrillation: a cohort study. Eur Heart J Qual Care Clin Outcomes. Published 14 June 2022. doi:10.
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