Congenital heart disease

Longitudinal Trends in Pediatric Survival by Congenital Heart Defect in Texas, 1999 to 2017

JACC AdvPublished population-based cohort study

Authors' conclusion

One-year survival improved for most CHDs over recent decades, although survival varies widely by CHD and characteristics. Findings have implications for clinical counseling, population-level resource and research planning, and reinforce the need for mitigation of disparities among individuals with CHDs.

Study context

Population
1999 to 2017 live births with ≥1 major CHD in the statewide Texas Birth Defects Registrychildren with CHDs
Participants
61,656 participants
Exposure
Survival by CHD lesion, birth period and characteristics
Outcome
Survival, all CHDs
Follow-up
7 days and 10 years

Main finding

As reported in the abstract

Survival at 7 days

98.1%

Survival at 10 years

90.7%

10-year survival range by lesion

50.0% to 97.3%

Observational data: associations, not effects.

Further findings

Born 1999-2004 vs born 2014-2017

1-year survival, hypoplastic left heart syndrome, by birth period

P < 0.0001

non-Hispanic Black mothers vs non-Hispanic White mothers

1-year survival, complex pulmonary atresia, by maternal race/ethnicity

P = 0.01

1-year survival, complex pulmonary atresia, by maternal race/ethnicity

One-year survival differed by sex, gestational age, birthweight, and extracardiac defect status

Original publication

Longitudinal Trends in Pediatric Survival by Congenital Heart Defect in Texas, 1999 to 2017. JACC Adv. Published 19 May 2025. doi:10.1016/j.jacadv.2025.101812

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