Aortic & peripheral vascular disease
Management strategies and outcomes in pregnancy-related acute aortic dissection: a multicentre cohort study in China
Study context
- Population
- Women with acute aortic dissection (AD) during pregnancy or within 12 weeks postpartum, 3 cardiovascular centres in China, 2003–2021
- Participants
- 67 women
- Exposure
- Selective surgery vs immediate surgery
Methodological detailsmulticentre, 3 cardiovascular centres in China
- Multicentre
- 3 cardiovascular centres in China
Main finding
As reported in the abstract
Maternal and fetal outcomes
Selective surgery vs Immediate surgeryAdjusted relative risk (95% CI)P value
Composite maternal and fetal death
12.47(3.26–47.73)
P = 0.0002Fetal death
8.77(2.33–33.09)
P = 0.001- Overall maternal mortality (7/67)
- 10.4%
- Overall fetal mortality (18/67)
- 26.9%
Observational data: associations, not effects.
Further findings
Patient characteristics
- Median age (years)
- 31
- Median gestation at AD onset (weeks)
- 32
- Type A AD (46 patients)
- 68.7%
- Type A AD with immediate surgery (n)
- 41
Original publication
Management strategies and outcomes in pregnancy-related acute aortic dissection: a multicentre cohort study in China. Heart. Published 12 September 2024. doi:10.
Summarised from the published abstract; every number is checked against it