Cardio-oncology & otherCohort study
Pregnancy, aortic events, and neonatal and maternal outcomes
- Retrospective cohort study
- nationwide database
Authors' conclusion
The association between pregnancy and aortic events was established in this study.
Study context
- Population
- Pregnancies and neonatal deliveries, Taiwan National Health Insurance Research Database, 2000–2020
- Participants
- 4,785,266 pregnancies
- Exposure
- Pregnancy vs control period; pregnancies with vs without aortic events
- Outcome
- Aortic events (association with pregnancy)
Main finding
As reported in the abstract
Aortic events
Vulnerable period
1.19 per 100 000 pregnancies
57 events
Control period
0.42 per 100 000 pregnancies
20 events
- Pregnancy a risk factor for aortic events (IRR), P < .001
- 2.86
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| 1-year maternal mortality, pregnancies with vs without aortic events | With aortic events 19.3% · Without aortic events 0.05% |
| Neonatal late mortality, maternal aortic events vs none | With aortic events 6.3% · Without aortic events 0.6% |
- 1-year maternal mortality, pregnancies with vs without aortic events: P < .001
- Neonatal late mortality, maternal aortic events vs none: P < .001
Original publication
Pregnancy, aortic events, and neonatal and maternal outcomes. Eur Heart J. Published 12 November 2024. doi:10.1093/eurheartj/ehae757
Summarised from the published abstract; every number is checked against it