Maternal Mortality and Cardio-Kidney-Metabolic Risk Factors Across High-Income Countries
Authors' conclusion
The U.S. women of reproductive age face a disproportionate burden of CVD, CKM factors, and maternal mortality rates compared with other high-income countries. Integrating early CVD and CKM screening and management into U.S. health care should be an urgent national priority.
Study context
- Population
- Women of reproductive age (15–49 years) in the United States compared with other high-income countries, 2003 to 2023
- Comparison
- The United States compared with other high-income countries
- Outcome
- CVD prevalence
- Follow-up
- 2003 to 2023
Main finding
As reported in the abstract
United States
3.7% to 3.1%
Further findings
- Cardiovascular disease (CVD) DALY rates · 2003 to 2023 — United States
- decline by 20%
- Maternal mortality rates · 2023 · highest compared to other high-income countries — United States
- 33.8 per 100,000 live births
- Mortality rates attributed to hypertensive disorders of pregnancy · 2023 · highest compared to other high-income countries — United States
- 2.8 per 100,000 live births
- Maternal mortality rates: Southern Latin America 65.2 per 100,000 live births
- Mortality rates attributed to hypertensive disorders of pregnancy: Southern Latin America 8.9 per 100,000 live births
CVD DALY rates · 2003 to 2023
- CVD burden remained higher than in other high-income countries
DALY rates attributable to cardio-kidney-metabolic (CKM) risk factors
- Body mass index >21 kg/m², United States vs other high-income countries
- 4-fold higher
- Fasting plasma glucose >95 mg/dL, United States vs other high-income countries
- 3-fold higher
- Systolic blood pressure >115 mm Hg, United States vs other high-income countries
- 2-fold higher
Original publication
Maternal Mortality and Cardio-Kidney-Metabolic Risk Factors Across High-Income Countries. JACC Adv. Published June 2026. doi:10.
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