Heart failure & cardiomyopathies
Meta-Analysis of Normal Reference Values for Right and Left Ventricular Quantification by Cardiovascular Magnetic Resonance
Authors' conclusion
Our Bayesian hierarchical meta-analysis provides normative reference values for CMR parameters of LV and RV size, systolic function, and mass, encompassing both tracing techniques across a diverse multinational sample of healthy men and women.
Study context
- Population
- Healthy adults; Cardiovascular magnetic resonance (CMR) SSFP short-axis stack at 1.5T or 3T; 25 countries
- Participants
- 12,812 adults254 studies
- Comparison
- Men vs Women
- Outcome
- Pooled lower and upper reference values for each CMR parameter (LV and RV size, systolic function, mass)
Methodological detailsBayesian hierarchical model, informative priors from external data set, published and unpublished data
- Bayesian hierarchical model
- Informative priors from external data set
- Published and unpublished data
Pooled result
As reported in the abstract
Pooled normative reference ranges
| Group | LVEF (papillary/trabeculations in left ventricular (LV) volume) | LV end-diastolic volume index (in LV volume) | LV end-systolic volume index (in LV volume) | LV mass index (in LV volume) | LVEF (papillary/trabeculations in LV mass) | LV end-diastolic volume index (in LV mass) | LV end-systolic volume index (in LV mass) | LV mass index (in LV mass) | Right ventricular (RV) EF | RV end-diastolic volume index | RV end-systolic volume index | RV mass index |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Men | 52% to 73% | 60 to 109 mL/m² | 18 to 45 mL/m² | 41 to 76 g/m² | 57% to 74% | 60 to 97 mL/m² | 18 to 37 mL/m² | 50 to 83 g/m² | 47% to 68% | 64 to 115 mL/m² | 23 to 52 mL/m² | 14 to 29 g/m² |
| Women | 54% to 75% | 56 to 96 mL/m² | 16 to 38 mL/m² | 33 to 57 g/m² | 57% to 75% | 55 to 88 mL/m² | 15 to 34 mL/m² | 38 to 65 g/m² | 49% to 71% | 57 to 99 mL/m² | 18 to 42 mL/m² | 13 to 25 g/m² |
LVEF (papillary/trabeculations in left ventricular (LV) volume)
Men52% to 73%
Women54% to 75%
LV end-diastolic volume index (in LV volume)
Men60 to 109 mL/m²
Women56 to 96 mL/m²
LV end-systolic volume index (in LV volume)
Men18 to 45 mL/m²
Women16 to 38 mL/m²
LV mass index (in LV volume)
Men41 to 76 g/m²
Women33 to 57 g/m²
LVEF (papillary/trabeculations in LV mass)
Men57% to 74%
Women57% to 75%
LV end-diastolic volume index (in LV mass)
Men60 to 97 mL/m²
Women55 to 88 mL/m²
LV end-systolic volume index (in LV mass)
Men18 to 37 mL/m²
Women15 to 34 mL/m²
LV mass index (in LV mass)
Men50 to 83 g/m²
Women38 to 65 g/m²
Right ventricular (RV) EF
Men47% to 68%
Women49% to 71%
RV end-diastolic volume index
Men64 to 115 mL/m²
Women57 to 99 mL/m²
RV end-systolic volume index
Men23 to 52 mL/m²
Women18 to 42 mL/m²
RV mass index
Men14 to 29 g/m²
Women13 to 25 g/m²
Original publication
Meta-Analysis of Normal Reference Values for Right and Left Ventricular Quantification by Cardiovascular Magnetic Resonance. Circ Cardiovasc Imaging. Published 20 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →