Microaxial Pump-Supported Coronary Surgery without Cardiopulmonary Bypass (CPB) to Optimize Outcome in Severely Impaired Left Ventricles
Authors' conclusion
MPCAB allows for complete surgical revascularization without the necessity of extracorporeal circulation in spite of severely impaired left ventricular function. This first comparative study on the outcome after MPCAB versus CPB-CABG demonstrates a significantly decreased risk of death as well as MACE in MPCAB patients. The MPCAB concept expands the spectrum of patients eligible for CABG without CPB towards patients with severely impaired left ventricular function.
Study context
- Population
- Patients suffering from three-vessel coronary artery disease with severely impaired left ventricular function, deemed appropriate for coronary artery bypass grafting (CABG) according to a heart team decision
- Comparison
- MPCAB versus CPB-CABG
- MPCABn = Eleven
- CPB-CABGn = 33
- Outcome
- Death from any cause
- Follow-up
- By the end of the (up to 4 years)
Main finding
As reported in the abstract
NNT
3
P = 0.0414
By group
Further findings
Additional mechanical circulatory support required
Major adverse cardiovascular events (MACE)
- Additional mechanical circulatory support required: P = 0.0363
- Major adverse cardiovascular events (MACE): P = 0.0189
Intraoperative and postoperative haemodynamics and revascularization
- MPCAB enabled continuous intraoperative and postoperative haemodynamic stabilization and complete myocardial revascularization
Baseline ejection fraction (MPCAB)
- Median ejection fraction
- 27%
Original publication
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