Acute cardiac care & resuscitation

Midterm Outcomes of Patients with Native Heart Recovery After Impella 5+ for Cardiogenic Shock

Eur J Heart FailPublished Retrospective cohort study

Authors' conclusion

Impella 5+ represents a promising treatment strategy for CS, providing high rates of sustained native heart recovery.

Study context

Population
Patients with cardiogenic shock supported by Impella 5+ and discharged with heart recovery, June 2022–April 2024
Participants
20 patients
Outcome
Survival and freedom from ICD, heart transplant/LVAD or readmission for HF
Follow-up
180 days
Methodological detailssingle-centre, Mean Impella support duration 10.5 ± 8 days
  • Single-centre
  • Mean Impella support duration 10.5 ± 8 days

Main finding

As reported in the abstract

Alive

19

95%

Heart transplant/LVAD

0

Implantable cardioverter-defibrillator (ICD) implanted

40%

HF admissions

2

Observational data: associations, not effects.

Further findings

Left ventricular ejection fraction (LVEF) · 180 days

Mean LVEF at 180 days
33.5 ± 10.7%
Mean LVEF before Impella
19.2 ± 5.2%

New York Heart Association (NYHA) class · 180 days

NYHA class I
5 (26.3%)
NYHA class II
9 (47.4%)
NYHA class III
5 (26.3%)

Original publication

Midterm Outcomes of Patients with Native Heart Recovery After Impella 5+ for Cardiogenic Shock. Eur J Heart Fail. Published 1 December 2024. doi:10.1002/ejhf.3544

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