Valvular & structural heart disease
Mitral Annular Calcification Score Determined by 3-D Transesophageal Echocardiography vs Cardiac Computed Tomography
Primary result · MAC score: correlation and agreement of 3D-TEE vs CTResult — go to the resultSpearman correlation coefficient 0.34Authors' conclusion
3D-TEE provides complementary and functionally relevant MAC assessment, correlating with MS severity.
Study context
- Population
- Patients with mitral annular calcification (MAC) undergoing transcatheter mitral valve replacement screening, 13 centres
- Participants
- 164 patients
- Comparison
- 3D-TEE vs computed tomography (CT) MAC score
Methodological detailsmulticentre, core laboratory assessment
- Multicentre
- Core laboratory assessment
Primary result
As reported in the abstract
MAC score: correlation and agreement of 3D-TEE vs CT
Spearman correlation coefficient
0.34
P < 0.001
By group
CT
8.0
mean · SD 0.44
3D-TEE
8.2
mean · SD 0.45
Further findings
Haemodynamics per unit increase in 3D-TEE MAC score
- 3D-TEE mitral valve area decrease
- 0.15 cm²
- 2D-TTE mitral valve area decrease
- 0.05 cm²
- Mean diastolic pressure gradient increase, 3D-TEE
- 1 mm Hg
- Mean diastolic pressure gradient increase, 2D-TTE
- 0.96 mm Hg
Regurgitation parameters vs 3D-TEE MAC score
- No significant correlation
Mitral stenosis (MS) and mitral regurgitation vs CT-MAC score
- Weak, nonsignificant correlations
Original publication
Mitral Annular Calcification Score Determined by 3-D Transesophageal Echocardiography vs Cardiac Computed Tomography. JACC Adv. Published 17 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →