Heart failure & cardiomyopathies
Mortality in Recipients of Durable Left Ventricular Assist Devices Undergoing Ventricular Tachycardia Ablation
Authors' conclusion
VT occurrence within 1 year of LVAD implantation was associated with worse survival. However, performance of VT ablation in this population was correlated with improved survival compared with medical management alone.
Study context
- Population
- Durable Left Ventricular Assist Device (LVAD) recipients, Baylor St. Luke's Medical Center and Texas Heart Institute, January 2011–January 202153% with post-implant ventricular tachycardia (VT)
- Participants
- 575 recipients
- Exposure
- VT ablation vs medical therapy alone in LVAD recipients with post-implant VT
- Outcome
- All-cause mortality
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
All-cause mortality, post-implant VT within 1 year · 45 months following VT onset
Hazard ratio (95% CI)
Catheter ablationvs Medical therapy alonesuperior survival with ablation
0.48(0.26–0.89)
Catheter ablationvs No post-implant VTmortality aligned with no post-implant VT
1.18(0.71–1.98)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Mortality with post-implant VT within 1 year of implantationvs withoutHigher mortality | 1.62 (1.15–2.27) | |
| 0.512Hazard ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Mortality in Recipients of Durable Left Ventricular Assist Devices Undergoing Ventricular Tachycardia Ablation. JACC Clin Electrophysiol. Published 17 July 2024. doi:10. 1016/ j. jacep. 2024. 04. 037
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