Heart failure & cardiomyopathies

Mortality in Recipients of Durable Left Ventricular Assist Devices Undergoing Ventricular Tachycardia Ablation

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

VT occurrence within 1 year of LVAD implantation was associated with worse survival. However, performance of VT ablation in this population was correlated with improved survival compared with medical management alone.

Study context

Population
Durable Left Ventricular Assist Device (LVAD) recipients, Baylor St. Luke's Medical Center and Texas Heart Institute, January 2011–January 202153% with post-implant ventricular tachycardia (VT)
Participants
575 recipients
Exposure
VT ablation vs medical therapy alone in LVAD recipients with post-implant VT
Outcome
All-cause mortality
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

All-cause mortality, post-implant VT within 1 year · 45 months following VT onset
Hazard ratio (95% CI)
Catheter ablationvs Medical therapy alonesuperior survival with ablation
0.48(0.26–0.89)
Catheter ablationvs No post-implant VTmortality aligned with no post-implant VT
1.18(0.71–1.98)

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)
Mortality with post-implant VT within 1 year of implantationvs withoutHigher mortality1.62 (1.15–2.27)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Mortality in Recipients of Durable Left Ventricular Assist Devices Undergoing Ventricular Tachycardia Ablation. JACC Clin Electrophysiol. Published 17 July 2024. doi:10.1016/j.jacep.2024.04.037

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.