Aortic & peripheral vascular disease
Multicenter Study on Physician-Modified Endografts for Thoracoabdominal and Complex Abdominal Aortic Aneurysm Repair
Authors' conclusion
PMEGs were a safe and effective treatment option for elective, symptomatic, and ruptured complex aortic aneurysms.
Study context
- Population
- Patients with complex abdominal or thoracoabdominal aortic aneurysms (elective, symptomatic or ruptured) treated with physician-modified endografts (physician modified endografts (PMEGs))
- Participants
- 1,274 patients19 centres
- Exposure
- Elective vs Symptomatic vs Ruptured
- Outcome
- Technical success (efficacy)
Methodological detailsinternational, 19 centres, Outcomes defined by Society for Vascular Surgery reporting standards
- International
- 19 centres
- Outcomes defined by Society for Vascular Surgery reporting standards
Main finding
As reported in the abstract
Technical success
- Overall technical success
- 94%
Observational data: associations, not effects.
Further findings
30-day mortality
- 30-day mortality — Overall 30-day mortality
- 5.8%
Freedom from reintervention · 1, 3 and 5 years
- 1 year
- 73.8%
- 3 years
- 61.8%
- 5 years
- 51.4%
- Median follow-up 21 months (5.6-50.6)
Primary target vessel patency · 1, 3 and 5 years
- 1 year
- 96.9%
- 3 years
- 93.6%
- 5 years
- 90.3%
Overall survival / freedom from aortic-related mortality · 1, 3 and 5 years
- 1 year
- 82.4%/92.9%
- 3 years
- 69.9%/91.6%
- 5 years
- 55.0%/89.1%
Safety
Major adverse events
- Major adverse events — Overall major adverse events
- 25.2%
Original publication
Multicenter Study on Physician-Modified Endografts for Thoracoabdominal and Complex Abdominal Aortic Aneurysm Repair. Circulation. Published 11 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →