Heart failure & cardiomyopathies

Multimodal Characterization of Dilated Cardiomyopathy: Geno- and Phenotyping of Primary Cardiomyopathy (GrAPHIC)

ESC Heart FailPublished Prospective observational cohort study

Authors' conclusion

The GrAPHIC will contribute to a better understanding of the heterogeneous nature of primary CMPs focusing on DCM and provide improved prognostic approaches and more individualized therapies.

Study context

Population
Patients with dilated cardiomyopathy (DCM) after exclusion of other causes (CAD, valvular dysfunction, myocarditis, toxin exposure, peripartum CMP), University Hospital Hamburg
Methodological detailsdesign paper, ongoing, monocentric, Clinical parameters, multimodal imaging and functional assessment, cardiac biopsies and blood samples obtained for integrated genomic, functional and biomarker analysis
  • Design paper
  • Ongoing
  • Monocentric
  • Clinical parameters, multimodal imaging and functional assessment, cardiac biopsies and blood samples obtained for integrated genomic, functional and biomarker analysis

Original publication

Multimodal Characterization of Dilated Cardiomyopathy: Geno- and Phenotyping of Primary Cardiomyopathy (GrAPHIC). ESC Heart Fail. Published 15 November 2023. doi:10.1002/ehf2.14544

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