Multimodality imaging in marantic endocarditis associated with cancer: a multicentric cohort study
Authors' conclusion
ME remains associated with a high risk of complications and death.
Study context
- Population
- Patients with marantic endocarditis associated with cancer, France and Belgium, 2011–2021
- Participants
- 47 patients
- Outcome
- Multimodality imaging in diagnosis of marantic endocarditis
Methodological detailsmulticentre, 4 tertiary endocarditis centres, November 2011 to August 2021
- Multicentre
- 4 tertiary endocarditis centres
- November 2011 to August 2021
Main finding
As reported in the abstract
- Vegetations detected by echocardiography
- all cases
- Vegetations detected by computed tomography (CT)
- 12 cases (26%)
- Increased cardiac 18F-FDG valve uptake
- 0
- 18FDG PET/CT performed
- 30 patients (64%)
- New cancer diagnosis by 18FDG PET/CT
- 14 patients (30%)
- Cancer diagnosed thanks to multimodality imaging
- 25 cases (54%)
Observational data: associations, not effects.
Further findings
Clinical characteristics
- Mean age, years
- 65 ± 11
- Native valves
- 43 cases (91%)
- Aortic valve involved
- 34 cases, 73%
- Known cancer before marantic endocarditis (ME)
- Twenty-two patients (46%)
- Treated medically with anticoagulation
- Forty-one patients (87%)
Systemic embolism
- Systemic embolism
- 40 patients, 85% of cases
Mortality · 1 year
- One-year mortality
- 55% (26 patients)
Original publication
Multimodality imaging in marantic endocarditis associated with cancer: a multicentric cohort study. Eur Heart J Cardiovasc Imaging. Published 14 June 2023. doi:10.
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