Coronary disease & ACS

Multivessel Coronary Function Testing Increases Diagnostic Yield in Patients With Angina and Nonobstructive Coronary Arteries

JACC Cardiovasc IntervPublished Diagnostic accuracy study

Authors' conclusion

Multivessel CFT resulted in an increased diagnostic yield in patients with ANOCA compared with single-vessel testing.

Study context

Population
Patients with suspected angina and nonobstructive coronary arteries (ANOCA)
Participants
80 patients228 vessels
Comparison
Multivessel vs single-vessel invasive coronary function testing
Outcome
Diagnostic yield (coronary vasomotor dysfunction)
Methodological detailsmulticentre
  • Multicentre

Performance

As reported in the abstract

Patients diagnosed with coronary vasomotor dysfunction

P = 0.0005

Further findings

Coronary artery spasm diagnosed

P = 0.004

CMD diagnosed

P < 0.001

Location of coronary artery spasm (n = 48)

Left coronary system
n = 38
Isolated right coronary spasm
20.8% (n = 10)

Number of vessels with coronary microvascular dysfunction (CMD) (CMD n = 50)

1-vessel CMD
27 (33.8%)
2-vessel CMD
15 (18.8%)
3-vessel CMD
8 (10%)

CMD by coronary territory

Left anterior descending
36.3%
Left circumflex
33.8%
Right coronary artery
31.3%
Similar rate across territories
P = 0.486

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Multivessel Coronary Function Testing Increases Diagnostic Yield in Patients With Angina and Nonobstructive Coronary Arteries. JACC Cardiovasc Interv. Published 13 May 2024. doi:10.1016/j.jcin.2024.03.007

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