Cardio-oncology & other

Myocardial Blood Flow Quantified Using Stress Cardiac Magnetic Resonance After Mild COVID-19 Infection

JACC AdvPublished Prospective comparative study

Authors' conclusion

This study suggests that there are no significant abnormalities in rest or stress myocardial perfusion, and thus microvascular function, in individuals after mild COVID-19 infection.

Study context

Population
Individuals after mild COVID-19 infection (none hospitalized)
Participants
30 vs 26
Exposure
Prior mild COVID-19 infection vs matched controls
  • Prior COVID-19n = 30
  • Controlsn = 26reference
Outcome
Myocardial blood flow (stress and rest myocardial blood flow (MBF)) and myocardial perfusion reserve by stress CMR
Methodological detailsmatched controls, Median time from infection to cardiac magnetic resonance (CMR) 5.6 (IQR: 4-8) months
  • Matched controls
  • Median time from infection to CMR 5.6 (IQR: 4-8) months

Main finding

As reported in the abstract

rMBF, sMBF and myocardial perfusion reserve
  • No significant differences in rMBF, sMBF or myocardial perfusion reserve between the groups
  • Prior COVID-19 vs Controls: P = 0.16
  • Prior COVID-19 vs Controls: P = 0.91
  • Prior COVID-19 vs Controls: P = 0.13
  • Values mean ± SD as printed; unpaired t-tests

Observational data: associations, not effects.

Further findings

Symptoms (chest pain, shortness of breath, syncope, palpitations)

P < 0.001

Original publication

Myocardial Blood Flow Quantified Using Stress Cardiac Magnetic Resonance After Mild COVID-19 Infection. JACC Adv. Published 7 February 2024. doi:10.1016/j.jacadv.2024.100834

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