Coronary disease & ACS

Myocardial infarction secondary to coronary embolism: aetiology, clinical characteristics, and prognosis

Eur Heart J Acute Cardiovasc CarePublished Retrospective cohort study

An erratum to this article was published (Eur Heart J Acute Cardiovasc Care, 8 Jul 2026 ↗)

Authors' conclusion

Coronary embolism is mostly caused by AF, usually presents with ST-segment elevation, and is associated with higher rates of mechanical complications and in-hospital embolic events, but not of recurrent thromboembolism after discharge. No significant differences in mortality were observed between CE and non-CE MI.

Study context

Population
Admissions for acute myocardial infarction (MI), single tertiary centre, January 2010–December 202389 (1.1%) with coronary embolism (CE)
Participants
8,160 patients
Exposure
Embolic MI vs non-embolic MI
  • CEn = 89
Outcome
Aetiology, clinical characteristics and prognosis of CE vs non-embolic MI
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

In-hospital outcomes, CE vs non-CE MI

Mechanical complications

P = 0.031

Stroke/TIA

P < 0.001

In-hospital mortality

P = 0.321

Observational data: associations, not effects.

Further findings

Attributable cause of CE

Atrial fibrillation (AF)
52.8%
Prosthetic valve thrombosis
11.2%
Endocarditis
7.9%

Presentation with ST-segment elevation, CE vs remaining patients

ST-segment elevation, CE vs remaining patients
79.8 vs. 58.6%, P < 0.001
CE more frequently female, lower prevalence of CV risk factors

Post-discharge outcomes (hospital survivors) · median follow-up 59.6 months

No differences in overall mortality or thrombo-embolic events after discharge
More HF admissions in the CE group
  • Propensity-matched analysis (77 in each group)

Original publication

Myocardial infarction secondary to coronary embolism: aetiology, clinical characteristics, and prognosis. Eur Heart J Acute Cardiovasc Care. Published 4 June 2025. doi:10.1093/ehjacc/zuaf081

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