Heart failure & cardiomyopathies
National Trends and Disparities in Heart Failure Hospitalizations and Inpatient Outcomes Between 2010-2022
Authors' conclusion
This longitudinal analysis of U.S. hospitalizations from 2010 to 2022 revealed that HF hospitalizations began increasing in 2014, peaked in 2019, and then declined sharply in 2020, a trend that persisted through 2022, with a more pronounced decline among adults aged >64 years.
Study context
- Population
- US adults hospitalized for heart failure (HF), 2010–2022
- Participants
- 14,287,733 weighted hospitalizations
- Exposure
- <65 years vs >64 years
- Outcome
- Age-standardized HF hospitalization rates and in-hospital mortality trends
- Follow-up
- 2010–2022
Methodological detailsNational Inpatient Sample database, age-standardized
- National Inpatient Sample database
- Age-standardized
Main finding
As reported in the abstract
Age-standardized HF hospitalizations per 100,000 US population
- 2010 to 2014: nonsignificant change, 406 to 381
- P = 0.14
- Increase to 447 in 2018
- P = 0.002
- Decline to 395 in 2022
- P = 0.002
- In-hospital mortality did not improve 2010–2022; significant uptrend in 2020 vs 2010-2019
- P = 0.001
Observational data: associations, not effects.
Further findings
| Outcome | <65 years | >64 years |
|---|---|---|
| HF hospitalizations by age group, 2010 to 2022 | ||
| Hospitalizations (2010 to 2022) | 124 to 161 | 1,775 to 1,525 |
| Average annual percentage change | 2.2 (95% CI: 1.6-2.8); P < 0.001 | −1.2 (95% CI: −2.8 to 0.9) |
Hospitalization rates by hospital location and insurer
- Declined at rural hospitals; increased among Medicare and Medicaid insurers
- P < 0.05
Original publication
National Trends and Disparities in Heart Failure Hospitalizations and Inpatient Outcomes Between 2010-2022. JACC Heart Fail. Published 1 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →