National Trends and Outcomes of Acute Myocardial Infarction After Transcatheter Aortic Valve Replacement
Authors' conclusion
There were no differences in the use of coronary revascularization for STEMI or NSTEMI in TAVR patients compared with the non-TAVR population. In-hospital mortality for STEMI is higher in TAVR patients compared with those without prior TAVR.
Study context
- Population
- Patients with STEMI or NSTEMI with or without prior transcatheter aortic valve replacement (TAVR), US Vizient Clinical Data Base, 2016–2022
- Participants
- 206,229 TAVR patients
- Exposure
- Prior TAVR vs no TAVR in patients with STEMI or NSTEMI
- Outcome
- Use of coronary angiography, revascularization and in-hospital outcomes
Methodological detailspropensity-score matched, national database
- Propensity-score matched
- National database
Main finding
As reported in the abstract
Coronary revascularization, by AMI type
- Use of coronary revascularization similar in prior TAVR and no TAVR cohorts
- Prior TAVR vs No TAVR: P = 0.81
- Prior TAVR vs No TAVR: P = 0.88
- After propensity matching
Observational data: associations, not effects.
Further findings
In-hospital mortality, STEMI (subgroup) · propensity matched
P = 0.03
In-hospital mortality, NSTEMI (subgroup) · propensity matched
P = 0.02
Incidence of acute myocardial infarction (AMI) after TAVR
- STEMI incidence
- 25 events per 100,000 person-years
- NSTEMI incidence
- 229 events per 100,000 person-years
- n = 206,229 TAVR patients
Original publication
National Trends and Outcomes of Acute Myocardial Infarction After Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv. Published 25 March 2024. doi:10.
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