Arrhythmias & electrophysiology
National Trends in Atrial Fibrillation Hospitalizations, Readmissions, and Mortality, 2010 to 2022
Authors' conclusion
In the United States, AF hospitalizations and readmissions experienced a modest overall net increase from 2010 to 2022, with a notable decline from 2014 to 2020 before rebounding following the COVID-19 pandemic, and 30-day readmissions and in-hospital mortality were associated with age, comorbidities, and socioeconomic factors.
Study context
- Population
- Primary atrial fibrillation (AF) hospitalizations in the United States, 2010 to 2022unique patients, 6,141,046 primary AF hospitalizations
- Participants
- 5,528,397 participants
- Outcome
- 30-day readmission and deaths during index admission
- Follow-up
- 2010 to 2022
Methodological detailscluster-adjusted multivariable logistic regression
- Cluster-adjusted multivariable logistic regression
Main finding
As reported in the abstract
30-day readmission
892,254
16.1%
Deaths during index admission
53,084
0.96%
Observational data: associations, not effects.
Further findings
Renal disease as predictor of 30-day readmission and in-hospital mortality
| Adjusted OR (95% CI) | ||
|---|---|---|
| Renal disease30-day readmission · strongest predictor of both outcomes | 1.39 (1.37–1.40) | |
| Renal diseaseIn-hospital mortality · strongest predictor of both outcomes | 3.98 (3.85–4.11) | |
| 0.20.5125Adjusted odds ratio (log scale) |
| Outcome | OR |
|---|---|
| Other factors associated with readmission and mortalityMedicare · readmission | 1.46 |
| Other factors associated with readmission and mortalityMedicare · mortality | 1.17 |
| Other factors associated with readmission and mortalityMedicaid · readmission | 1.62 |
| Other factors associated with readmission and mortalityMedicaid · mortality | 1.43 |
| Other factors associated with readmission and mortalityChronic obstructive pulmonary disease · readmission | 1.48 |
| Other factors associated with readmission and mortalityChronic obstructive pulmonary disease · mortality | 1.66 |
| Other factors associated with readmission and mortalityHeart failure · readmission | 1.38 |
| Other factors associated with readmission and mortalityHeart failure · mortality | 1.83 |
| Other factors associated with readmission and mortalityPrior myocardial infarction · readmission | 1.26 |
| Other factors associated with readmission and mortalityPrior myocardial infarction · mortality | 3.34 |
| Other factors associated with readmission and mortalityFemale sex · readmission | 1.12 |
| Other factors associated with readmission and mortalityFemale sex · mortality | 1.07 |
Other factors associated with readmission and mortality
- Lower income quartile associated with adverse outcomes
Total cost of AF hospitalizations · 2022
- Total cost
- $7.2 billion
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →