Heart failure & cardiomyopathies
Non-Dilated Left Ventricular Cardiomyopathy vs. Dilated Cardiomyopathy: Clinical Background and Outcomes
Authors' conclusion
There was no significant difference in the incidence of cardiac events between NDLVC-REF and DCM. Among NDLVC-REF patients, 18% of patients who showed LV dilatation after diagnosis had poor outcomes.
Study context
- Population
- Patients with newly diagnosed non-ischaemic cardiomyopathy and reduced LVEF (<50%), December 2004–January 201844 with cardiac events
- Participants
- 363 patients
- Exposure
- NDLVC-REF vs dilated cardiomyopathy (DCM)
- NDLVC-REFn = 80
- Outcome
- Cardiac events:
- SCD
- Rehospitalization for HF
- Follow-up
- Median 68.8 months (IQR 33.0-93.7)
Main finding
As reported in the abstract
Cardiac events (Kaplan-Meier) · median 68.8 months
- NDLVC-REF vs DCM: P = 0.349
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Cardiac events, NDLVC-REF with vs without LV dilatation after diagnosis (subgroup)Higher risk with LV dilatation (14% of NDLVC-REF) | P = 0.049 |
Baseline characteristics
- Higher prevalence of AF and higher LVEF in NDLVC-REF than DCM
LVEF and LV end-diastolic diameter · all time points after diagnosis
- Higher LVEF and smaller LV end-diastolic diameter in NDLVC-REF than DCM
Original publication
Non-Dilated Left Ventricular Cardiomyopathy vs. Dilated Cardiomyopathy: Clinical Background and Outcomes. ESC Heart Fail. Published 6 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →