Valvular & structural heart disease
Non-invasive myocardial work in aortic stenosis: validation and improvement in left ventricular pressure estimation
Authors' conclusion
This study confirms the validity of the non-invasive MWI in patients with AS. The accuracy of estimated LVP curves improved when matching AVO to the diastolic pressure in the original model, mirroring that of the AS-specific model.
Study context
- Population
- Patients with severe aortic stenosis (AS)
- Participants
- 20 patients
- Comparison
- Estimated left ventricular pressure (LVP) vs invasive LVP for non-invasive myocardial work index
- Outcome
- Agreement of estimated vs invasive LVP and MWI
Methodological detailssame-beat comparison of invasive and estimated LVP
- Same-beat comparison of invasive and estimated LVP
Performance
As reported in the abstract
Model 1 overestimated early systolic pressure at aortic valve opening (AVO) vs Models 2 and 3 (significant)
61 ± 5 mmHg
Correlation of myocardial work index (MWI) with estimated (all models) vs invasive LVP; good agreement
r = 0.98
P < 0.001
Original publication
Non-invasive myocardial work in aortic stenosis: validation and improvement in left ventricular pressure estimation. Eur Heart J Cardiovasc Imaging. Published 6 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →