Case-control study
Noninvasive In Vivo Coronary Artery Thrombus Imaging
- Case-control study
- single-centre
- observational
Authors' conclusion
Coronary 18F-GP1 PET/CT angiography is the first noninvasive selective technique to identify in vivo coronary thrombosis in patients with acute myocardial infarction.
Study context
- Population
- Patients with or without acute MI undergoing coronary 18F-GP1 positron emission tomographic (PET)/computed tomographic (CT) angiography
- Participants
- 49 vs 50
- Comparison
- Acute MI vs no acute MI
- With acute myocardial infarctionn = 49
- Without acute myocardial infarctionn = 50reference
- Outcome
- Coronary 18F-GP1 uptake (visual and maximum target-to-background ratio)
Main finding
As reported in the abstract
Coronary 18F-GP1 uptake in culprit lesions
Acute MI
80%
39 events
Observational data: associations, not effects.
Further findings
Determinants of 18F-GP1 uptake (multivariable regression)
- Culprit vessel status the only independent variable associated with higher 18F-GP1 uptake
Extracoronary cardiac 18F-GP1 findings
- Infarct-related intramyocardial uptake
- 35%
- LV thrombus
- 8%
- Left atrial thrombus
- 2%
Original publication
Noninvasive In Vivo Coronary Artery Thrombus Imaging. JACC Cardiovasc Imaging. Published 14 December 2022. doi:10.1016/j.jcmg.2022.10.002
Summarised from the published abstract; every number is checked against it