On-treatment blood pressure and cardiovascular mortality in adults with repaired coarctation of aorta
Authors' conclusion
Collectively, these data suggest that even s less severe form of hypertension SBP (120-129 mmHg) was not benign
Study context
- Population
- Adults with repaired coarctation of aorta on antihypertensive therapyage 39 ± 11
- Participants
- 461 adults
- Exposure
- Higher vs lowest on-treatment systolic BP (SBP) quartile
- Outcome
- CV mortality
Main finding
As reported in the abstract
Each group vs lowest SBP quartileHazard ratio (95% CI)
SBP 120-129
1.05(1.01–1.07)
SBP 130-139
1.12(1.04–1.15)
SBP ≥140
1.39(1.13–1.59)
Observational data: associations, not effects.
Further findings
CV mortality per 5 mmHg increase in blood pressure (BP)
- Increase in risk per 5 mmHg increase in SBP
- 7%
- Increase in risk per 5 mmHg increase in DBP
- 4%
Original publication
On-treatment blood pressure and cardiovascular mortality in adults with repaired coarctation of aorta. Am Heart J. Published 8 October 2022. doi:10. 1016/ j. ahj. 2022. 10. 008
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