Coronary disease & ACS

One-month DAPT with ticagrelor and aspirin for patients undergoing coronary artery bypass grafting: rationale and design of the randomised, multicentre, double-blind, placebo-controlled ODIN trial

EuroInterventionPublished Randomised controlled trial

Study context

Population
Patients with chronic coronary syndromes undergoing coronary artery bypass graft (CABG)planned
Participants
700 patients
Planned comparison
Ticagrelor + aspirin for 1 month vs placebo + aspirin after CABG
Primary endpoint
Hierarchical composite of:
  1. All-cause death
  2. Stroke
  3. MI
  4. Revascularisation
  5. Graft failure
Follow-up
1 year
Methodological detailsrationale and design, double-blind, placebo-controlled, international, multicentre, prospective, Randomised 1:1
  • Rationale and design
  • Double-blind
  • Placebo-controlled
  • International
  • Multicentre
  • Prospective
  • Randomised 1:1

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

One-month DAPT with ticagrelor and aspirin for patients undergoing coronary artery bypass grafting: rationale and design of the randomised, multicentre, double-blind, placebo-controlled ODIN trial. EuroIntervention. Published 4 March 2024. doi:10.4244/eij-d-23-00699

Summarised from the published abstract; every number is checked against it

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