Aortic & peripheral vascular disease
Operative Mortality After Type A Aortic Dissection Surgery: Differences Based on Sex and Age
Main finding · Operative mortalityResult — go to the resultAdjusted odds ratio 1.334 95% CI 0.918–1.938Authors' conclusion
Under the age of 55 years, females have similar odds of operative mortality compared with males; however, over the age of 55 years females have higher odds than males.
Study context
- Population
- Consecutive patients with surgically repaired acute type A aortic dissection (ATAAD), multicentre China 5A study
- Participants
- 5,670 patients
- Exposure
- Females vs males
- Femalesn = 1,503
- Malesn = 4,167reference
- Outcome
- Operative mortality
- Follow-up
- 30-day
Methodological detailsmulticentre, propensity analyses
- Multicentre
- Propensity analyses
Main finding
Operative mortality
Adjusted odds ratio
1.334
95% CI 0.918–1.938
By group
Females vs Males
adjusted OR 1.334 (95% CI 0.918–1.938)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Operative mortality per year of age, by sex — Females · older age, females | 1.045 (1.029–1.061) | |
| Operative mortality per year of age, by sex — Males · older age, males | 1.025 (1.016–1.035) | |
| Operative mortality by age <55 vs >55 years (subgroup) — Females vs Males · under 55 years | 0.852 (0.603–1.205) | |
| Operative mortality by age <55 vs >55 years (subgroup) — Females vs Males · over 55 years | 1.420 (1.096–1.839) | |
| 0.512Odds ratio (log scale) |
- Operative mortality per year of age, by sex: sex × age P interaction = 0.035
- Operative mortality by age <55 vs >55 years (subgroup): P interaction = 0.019
Original publication
Operative Mortality After Type A Aortic Dissection Surgery: Differences Based on Sex and Age. JACC Adv. Published 14 March 2024. doi:10.
Summarised from the published abstract; every number is checked against it