Valvular & structural heart disease

Optimizing patient triage on the waiting list for transcatheter aortic valve replacement: the clinical utility of the cardiac damage staging system

Eur Heart J Qual Care Clin OutcomesPublished retrospective, single-center, longitudinal study

An erratum to this article was published (Eur Heart J Qual Care Clin Outcomes, 23 Jun 2026 ↗)

Authors' conclusion

These findings suggest that TAVR candidates at Généreux stages 3 and 4 should receive higher priority on the waiting list.

Study context

Population
Patients referred for transcatheter aortic valve replacement (TAVR)patients who died while on the TAVR waiting list
Participants
98 patients
Outcome
All-cause mortality from the time of a patient’s inclusion on the TAVR waiting list or non-proceeding to TAVR

Main finding

As reported in the abstract

Overall proportion of deceased patients
8.4% [95% confidence interval (CI), 6.9-10.1]
Proportion of deceased patients when excluding deaths occurring after 2019
4%
Deaths by 3 months
6.3%
Deaths by 6 months
7.8%
Deaths that took place within the first 3 months
90%

Observational data: associations, not effects.

Further findings

Variables independently associated with mortality on the TAVR waiting list (multivariable analysis)

sHR (95% CI)P value
Prior myocardial infarction1.87 (1.12–3.13)P = 0.017
Pulmonary artery systolic pressure > 60 mmHg2.37 (1.36–4.12)P = 0.002
Généreux stages 3 and 4More than doubling the risk of death2.12 (1.33–3.38)P = 0.002

Patients who had undergone TAVR

By 3 months
61.2%
At 6 months
85.4%

Original publication

Optimizing patient triage on the waiting list for transcatheter aortic valve replacement: the clinical utility of the cardiac damage staging system. Eur Heart J Qual Care Clin Outcomes. Published 3 March 2026. doi:10.1093/ehjqcco/qcag001

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.