Heart failure & cardiomyopathies
Optimizing Triage of Ambulatory Patients With Advanced Heart Failure: 2-Year Outcomes From REVIVAL
Authors' conclusion
REVIVAL patients not selected for VAD or transplant have robust survival and patient-reported outcomes, which challenges advocacy for earlier VAD implantation.
Study context
- Population
- Ambulatory patients with advanced systolic heart failure (HF) on guideline-directed medical therapy (GDMT), ≥1 HF mortality risk marker, no left ventricular assist device (LVAD) contraindication
- Participants
- 400 patients21 LVAD centers
- Outcome
- Death, durable ventricular assist device, or urgent transplant
- Follow-up
- 2 years
Methodological detailsmulticentre (21 LVAD centers)
- Multicentre (21 LVAD centers)
Main finding
As reported in the abstract
Composite primary outcome · 1 and 2 years
Composite primary outcome at 1 year
22%
Composite primary outcome at 2 years
37%
Observational data: associations, not effects.
Further findings
Death alone · 1 and 2 years
- Death at 1 year
- 8%
- Death at 2 years
- 16%
GDMT intensity and health-related quality of life in 2-year survivors
- Maintained GDMT intensity and no decline in health-related quality of life
Original publication
Optimizing Triage of Ambulatory Patients With Advanced Heart Failure: 2-Year Outcomes From REVIVAL. JACC Heart Fail. Published 3 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →