Heart failure & cardiomyopathies

Racial Inequities in Access to Ventricular Assist Device and Transplant Persist After Consideration for Preferences for Care: A Report From the REVIVAL Study

Circ Heart FailPublished Prospective observational cohort study

Main finding · VAD or transplant; deathResult — go to the resultAdjusted hazard ratio 0.45 95% CI 0.23–0.85

Authors' conclusion

Among patients receiving care by advanced HF cardiologists at VAD centers, there is less utilization of VAD and transplant for Black patients even after adjusting for HF severity, quality of life, and social determinants of health, despite similar care preferences.

Study context

Population
Ambulatory chronic systolic heart failure (HF) patients with high-risk features and no contraindication to ventricular assist device (VAD) at 21 VAD centres
Participants
377 patients21 VAD centres
Exposure
Black vs White race
  • Blackn = 100
Outcome
(1) VAD/transplant and (2) death
Follow-up
2 years
Methodological detailsmulticentre, competing events cause-specific proportional hazards, multiple imputation
  • Multicentre
  • Competing events cause-specific proportional hazards
  • Multiple imputation

Main finding

VAD or transplant; death

Adjusted hazard ratio

0.45

95% CI 0.23–0.85

By group

Black

VAD or transplant
11 (11%)
Death
18 (18%)

White

VAD or transplant
62 (22%)
Death
36 (13%)

VAD or transplant

Black11 (11%)
White62 (22%)

Death

Black18 (18%)
White36 (13%)
Blackvs White
adjusted HR 0.45 (95% CI 0.23–0.85)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Preferences for VAD or life-sustaining therapies

Similar by race; did not explain racial disparities

Original publication

Racial Inequities in Access to Ventricular Assist Device and Transplant Persist After Consideration for Preferences for Care: A Report From the REVIVAL Study. Circ Heart Fail. Published 19 October 2022. doi:10.1161/circheartfailure.122.009745

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