Ostial right coronary artery lesion morphology and outcomes after treatment with drug-eluting stents
Main finding · TLF (Kaplan-Meier rate)Result — go to the resultHazard ratio 6.63 95% CI 1.28–34.3Authors' conclusion
Ostial RCA lesions have specific morphologies - detectable by IVUS - that may be associated with long-term clinical outcomes.
Study context
- Population
- De novo ostial right coronary artery (RCA) stenoses (within 3 mm of aorto-ostium) treated with percutaneous coronary intervention (PCI), imaged by intravascular ultrasound (IVUS)
- Participants
- 170 ostial RCA stenoses
- Exposure
- Ostial RCA lesion morphologies: isolated vs ostial CN vs diffuse disease
- Isolatedn = 20
- Ostial CNn = 81
- Diffusen = 69reference
- Outcome
- TLF (cardiac death, target vessel MI, definite stent thrombosis, ischaemia-driven target lesion revascularisation)
- Follow-up
- 2 years
Methodological detailsIVUS-based
- IVUS-based
Main finding
TLF (Kaplan-Meier rate)
Hazard ratio
6.63
95% CI 1.28–34.3
P = 0.02
Events by group
CN
HR 6.63 (95% CI 1.28–34.3); P = 0.02
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Isolated | Ostial CN | Diffuse | P value |
|---|---|---|---|---|
| WomenIsolated vs Diffuse | 75.0% | — not stated in the abstract | 42.0% | P = 0.01 |
| AgeOstial CN vs Diffuse · median, years | — not stated in the abstract | 76 (first, third quartile 70–83) | 69 (first, third quartile 63–81) | P = 0.002 |
— not stated in the abstract
Original publication
Ostial right coronary artery lesion morphology and outcomes after treatment with drug-eluting stents. EuroIntervention. Published 5 February 2024. doi:10.
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