Outcomes among patients with coronary bifurcation lesions undergoing Impella-supported high-risk percutaneous coronary intervention
Authors' conclusion
While patients with CBLs undergoing Impella-supported high-risk PCI had higher complexity, there were similar rates of PCI-related complications and 90-day MACCE.
Study context
- Population
- Patients undergoing Impella-supported high-risk percutaneous coronary intervention (PCI)
- Participants
- 1,044 patients
- Comparison
- True coronary bifurcation lesions (CBL) vs nontrue CBL and/or no CBL
- Primary endpoint
- CEC-adjudicated MACCE:
- All-cause death
- MI
- Stroke/TIA
- Repeat revascularization
- Follow-up
- 90 days
Methodological detailsFDA-audited
- FDA-audited
Primary result
As reported in the abstract
90-day MACCE
- Similar rates of 90-day MACCE with CBLs after adjustment
- Adjusted for age, sex, left main disease, triple vessel disease
Further findings
Procedural complexity
- CBLs: significantly higher pre-PCI SYNTAX score and number of treated lesions, more left main and triple vessel disease, longer procedure duration
- No difference in post-PCI SYNTAX score or failure to achieve angiographic success
Safety
- No difference in PCI-related complications
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Outcomes among patients with coronary bifurcation lesions undergoing Impella-supported high-risk percutaneous coronary intervention. Am Heart J. Published 22 May 2025. doi:10.
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