Pulmonary vascular disease & thromboembolism
Outcomes with catheter-directed thrombolysis vs. catheter-directed embolectomy among patients with high-risk pulmonary embolism: a nationwide analysis
Authors' conclusion
In this contemporary observational analysis of patients admitted with high-risk PE undergoing CDT or CDE, the rates of in-hospital mortality, ICH, and non-ICH bleeding events were not different.
Study context
- Population
- Hospitalizations with high-risk pulmonary embolism (PE) undergoing catheter-directed interventions, Nationwide Readmissions Database, 2016–2019484 (15%) received both
- Participants
- 3,216 hospitalizations
- Exposure
- Catheter-directed thrombolysis (CDT) vs catheter-directed embolectomy (CDE)
- CDTn = 1,864reference
- CDEn = 868
- Outcome
- All-cause in-hospital mortality
- Follow-up
- In-hospital
Methodological detailspropensity-score matched, nationwide database
- Propensity-score matched
- Nationwide database
Main finding
As reported in the abstract
P = 0.07
Observational data: associations, not effects.
Further findings
Length of stay, cost, 30-day unplanned readmissions
- No differences between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Outcomes with catheter-directed thrombolysis vs. catheter-directed embolectomy among patients with high-risk pulmonary embolism: a nationwide analysis. Eur Heart J Acute Cardiovasc Care. Published 4 February 2023. doi:10.
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