Arrhythmias & electrophysiology

Outcomes of Concomitant Atrial Fibrillation Ablation and Left Atrial Appendage Closure: A Retrospective Single-Center Experience

JACC AdvPublished Retrospective observational study

Study context

Population
Patients undergoing concomitant atrial fibrillation (AF) ablation and left atrial appendage closure (LAAC), June 2015–August 2021
Participants
178 patients
Outcome
Safety and efficacy: procedural success, periprocedural complications, thromboembolism, bleeding, arrhythmia recurrence
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

median follow-up 412 days (IQR 213 to 781)
Pulmonary vein isolation achieved
all patients
LAAC aborted
15 cases
LAAC success rate
91.6%
Strokes
2
TIAs
3
Annual stroke/TIA risk at 1 year
1.7%
Annual stroke/TIA risk at 2 years
4.6%
Complete seal intraprocedurally
97.5%
Complete seal on initial follow-up (no major leaks)
73.7%
Anticoagulation discontinued
93.8%

Observational data: associations, not effects.

Safety

Periprocedural complications

Periprocedural complications rate
6.2%

Device-related thrombus

Device-related thrombus, resolved with anticoagulation
2 cases (1.3%)

Bleeding

Bleeding events
34
Patients with bleeding
28 (17.4%)

LAAC aborted

LAAC aborted (success rate 91.6%)
15 cases

Original publication

Outcomes of Concomitant Atrial Fibrillation Ablation and Left Atrial Appendage Closure: A Retrospective Single-Center Experience. JACC Adv. Published 14 November 2024. doi:10.1016/j.jacadv.2024.101377

Composed by AI from the published abstract and checked against it. How Briefs are made →

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