Acute cardiac care & resuscitation

Outcomes of extracorporeal life support in hypothermic cardiac arrest: Revisiting Extracorporeal Life Support Organization (ELSO) guidelines

ResuscitationPublished Retrospective cohort study

Authors' conclusion

Qualification of patients with hypothermic cardiac arrest for ECLS rewarming should not be strictly based on guidelines for normothermic cardiac arrest, as this may result in not initiating potentially life-saving treatment for patients who could have favourable prognoses for survival with good neurological outcomes.

Study context

Population
Patients with hypothermic cardiac arrest (HCA) treated with extracorporeal life support (ECLS)
Participants
127 patients
Exposure
ECLS in HCA patients meeting vs not meeting ELSO eligibility criteria
  • Meeting ELSO criterian = 62reference
  • Not meeting ELSO criterian = 65
Outcome
Survival to hospital discharge and favourable neurological outcome
Follow-up
Hospital discharge
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Survival to hospital discharge
GroupValueFavourable neurological outcome among survivors
Met ELSO criteria61 %34 (89 %)
Not meeting ELSO criteria37 %20 (83 %)

Value

Met ELSO criteria61 %
Not meeting ELSO criteria37 %

Favourable neurological outcome among survivors

Met ELSO criteria34 (89 %)
Not meeting ELSO criteria20 (83 %)

Observational data: associations, not effects.

Further findings

Survival by number of ELSO criteria not met (subgroup) · hospital discharge

Favourable neurological outcome among survivors

Survival by number of ELSO criteria not met (subgroup) · hospital discharge

The two patients who failed to meet all three ELSO criteria did not survive

Original publication

Outcomes of extracorporeal life support in hypothermic cardiac arrest: Revisiting ELSO guidelines. Resuscitation. Published 5 November 2024. doi:10.1016/j.resuscitation.2024.110424

Composed by AI from the published abstract and checked against it. How Briefs are made →

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